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The lethal dose threshold (LD1) was never achieved in animal safety studies meaning researchers could not identify a dose lethal to 1% of test subjects
The standard dose escalation protocol Based on the Phase 2 clinical trial data published in the New England Journal of Medicine, the typical retatrutide dose schedule follows a pattern like this: During the starting phase, a single 10mg vial reconstituted with 2mL of bacteriostatic water can last up to 10 weeks at a 1mg weekly dose
Patients with pre-existing conditions including cardiovascular disease, liver disease, thyroid disorders, kidney disease, or gallbladder disease face particular uncertainty