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The common side effects identified by experts include nausea and vomiting, diarrhoea, dizziness and headaches, and discolouration of the skin and nails
Clinical evidence: key trials and outcomes The kidney-protective potential of SGLT2 inhibitors was first identified in cardiovascular outcome trials, including Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus PatientsRemoving Excess Glucose (EMPA-REG OUTCOME) [36], Canagliflozin Cardiovascular Assessment Study (CANVAS) [37], and Dapagliflozin Effect on Cardiovascular EventsThrombolysis in Myocardial Infarction 58 (DECLARETIMI 58) [38]
The SURMOUNT trial series showed tirzepatide recipients achieved reductions up to 22% of baseline body weight at the highest maintenance doses
These nutrients may include: Nicotinamide adenine dinucleotide (NAD) Glutathione B-complex vitamins How long does treatment take
Do not aspirate for subcutaneous injections (aspiration is not required and may increase discomfort) [13]
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