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Interestingly, stepwise-administration of amylin and GLP-1R analogs overall resulted in the greatest and longest-lasting suppression of food intake and body weight in DIO-rats across the treatment-period
Starkey M, Lepine F, Maura D, Bandyopadhaya A, Lesic B, He J, et al
Most treatments tackle one of those
It achieved an average weight log of 13.6% at 64 weeks in the OASIS 4 trial
This combination is actually quite common in clinical practice, as both medicines address different aspects of cardiometabolic health that frequently coexist in the same individuals
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