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Gastroenterology 141 , 237248 (2011)
Obes Surg 31(4):17551766 Nedelcu M, Khwaja HA, Rogula TG (2016) Weight regain after bariatric surgery-how should it be defined
Tirzepatide's GIP co-agonism appears to protect against diarrhea relative to semaglutide, even at higher weight loss
The problem was the side effects associated, particularly with GLP-1, are what we call peak to trough: so the difference between the highest amount of drug and the lowest and then going back up again to the highest caused by this twice-a-day dosingwhich you can imagine someone bouncing around maybe two to three times, the drug at peak, then trough, causes a lot of GI distress
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