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Safety across the full program was consistently favorable: adverse events, primarily mild headache and gastrointestinal symptoms, occurred at rates comparable to placebo, with no treatment-related discontinuations, no IGF-1 elevation, and no impact on glucose metabolism
S.Gutirrez-De-TernH.qvistJ
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GLP-1 agonists reduce LDL-C and ameliorate ox-LDLs proinflammatory injurious effects on vascular endothelial cells that include monocyte binding [59]
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