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It is also approved to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease (Ozempic), and in adults with established cardiovascular disease and either obesity or overweight (Wegovy)
465 (Fig
N Engl J Med 370(15):13831392 Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ et al (2003) Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved trial
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In some cases, temporary discontinuation of Zepbound may be necessary while psychiatric symptoms are addressed, though this decision requires careful risk-benefit analysis
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