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These drugs work by mimicking the action of certain hormonesprimarily GLP-1 (glucagon-like peptide-1)that play a key role in regulating blood sugar and appetite
There is growing evidence supporting the effectiveness of GLP-1 receptor agonists (GLP-1 RAs) for weight management ( 1 3 ), including some of our own Truveta research
This suggests that the chemical modifications enhancing their stability may simultaneously limit their access to central GLP-1Rs
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In clinical settings, they often lead to reduced food intake and steady weight loss
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