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Early gestational diabetes is associated with worse pregnancy outcomes compared to women diagnosed with late gestational diabetes (hyperglycaemia typically from 24 weeks to 28 weeks of gestation)
In clinical trials, tirzepatide produced greater average weight loss, roughly 20% compared to about 14% of body weight over 72 weeks
list price is about $1,349 per month, far out of reach for many uninsured or underinsured patients
The serious adverse event rate with tirzepatide is low
Melatonin: a universal time messenger [PMID: 26313381] Laboratory literature summary: Melatonin: a universal time messenger
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