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The length of the SSRs, when located within a coding region, can change translation by introducing a frameshift in the reading frame, or, when located in the proximity of a promoter, can modulate transcription either by altering the promoter sequence or by switching between alternative promoter sites
Potentiation of glucose-induced insulin secretion by GIP is diminished in chronic hyperglycaemic states due at least in part to a decrease in the Gs subtype of the GIP receptor in pancreatic beta cells, and further reasons for concern over GIP as a treatment for type 2 diabetes are that it increases glucagon secretion and adipose deposition [49]
This usually subsides quickly
They are not meant to treat chronic conditions or provide long-term care
This correlation between GLP-1-based therapies and mental well-being is important in understanding the intersecting realms of diabetes management and mental health
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