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Semaglutide is a GLP-1 receptor agonist, the same class of medication marketed under brand names like Ozempic and Wegovy
We hypothesize that the influence of SFN on the gut microbiota is at least partly related to the effects on their habitat, i.e., the gut such as (i) alleviation of oxidative stress and inflammation in the intestine, (ii) increase of the expression of tight junction proteins, preventing excessive intestinal permeability and invasion of luminal bacteria, and (iii) promotion of gut detoxification capability via increase of activity of phase II detoxification enzymes such as GSTs
Your provider will ask about your heart, liver, kidneys, hormones, and any past or current cancers or serious illnesses
Use of incretin-based drugs and risk of cholangiocarcinoma: Scandinavian cohort study