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Valeriano V, Balolong M, Kang DK

suggest that the biopsy sample of lingual melanotic lesions include normal tissue so that it is easier to compare the normal pigmentation with that of the lesion.2 Although lingual melanotic macule is a benign condition, an important differential diagnosis is made with melanoma

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Low-grade inflammation can stress blood vessels and speed up plaque activity, even when symptoms are subtle or absent

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