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Bitter compounds activate taste receptors not only on the tongue, but also throughout the gastrointestinal tract, where they can stimulate the release of incretin hormones like GLP-1
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Agonist treatment of either control- or hGPR17L-transduced cells had no effect on PGE 2 -stimulated GLP-1 secretion as compared to vehicle treatment (Figure 6C)
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Chickpeas, tuna, potatoes and bulgur are dietary sources to consider
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