This common concern affects many patients starting glucagon-like peptide-1 (GLP-1) receptor agonists like semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), or dulaglutide (Trulicity) for type 2 diabetes or weight management
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Do not use Wegovy if: You or a family member have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) [3] You have had a serious allergic reaction to semaglutide or any of the ingredients in Wegovy If youre pregnant or breastfeeding [3] For more information, please reach out to your healthcare provider
Liraglutide has anti-inflammatory effects on endothelial cells by decreasing activation of NF-kB, inhibiting TNF-alpha, and increasing nitric oxide production (28)
In sum, employers should take extra caution when considering GLP-1 coverage for some conditions, but not others