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Historically, the uses of glutathione were mainly medical, based around its role in cellular defence and metabolism
Overactivated HER2 signaling results in increased HIF-1 and VEGF expression, which in turn activate the downstream kinase FKBP-rapamycin-associated protein (FRAP), therefore contributing to tumor progression by mediating angiogenesis and metabolic adaptation (221)
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*Correspondence: Hyunju Kang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Together they target distinct aspects of tissue regeneration: GHK-Cu addresses matrix synthesis and structural integrity, while BPC-157 ensures adequate blood supply and growth factor signalling
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