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TABLE 2 provides a summary of key information from PIONEER 1-8

Unlike DAMPs, which are not derived from infectious pathogens and initiate infection-related inflammation, PAMPs originate from the invasion by foreign substances and infections caused by microorganisms or viruses (Hemmi et al., 2000)

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RNA extraction, cDNA synthesis and real-time quantitative PCR (RT-qPCR) Total RNA was isolated from cells using a TRI Reagent kit (Sigma) according to the manufacturers instructions

Proof of concept: effect of GLP-1 agonist on food hedonic responses and taste sensitivity in poor controlled type 2 diabetic patients