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The peptide works exclusively through peripheral mechanisms in adipose (fat) tissue rather than through central nervous system pathways that regulate appetite and feeding behavior

Monitoring renal function is advisable, particularly in patients experiencing significant gastrointestinal symptoms that could lead to dehydration

10.1002/(SICI)1096-9101(1996)19:3 3.0.CO;28 90 RadeljakS.SeiwerthS.SikiricP

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