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Regarding safety profile, in phase 2 trials for obesity and diabetes, mazdutide was discontinued due to AE by 02% of participants and SAE experienced by up to 7% of participants with mazdutide 6 mg (Tables 2 and 3)
A randomized controlled trial published in the New England Journal of Medicine demonstrated that tesamorelin significantly reduced visceral adipose tissue in patients with abdominal fat accumulation (Falutz et al., 2007)
Endocrinology Reviews, 35(7), 890-905
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