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Specifically, we used genetic variants to predict l-carnitine, and obtained their associations with coronary artery disease (CAD), ischemic stroke, heart failure, and atrial fibrillation, as well as CVD risk factors (type 2 diabetes, glucose, HbA1c, insulin, lipid profile, blood pressure and body mass index) in large consortia and established cohorts, as well as sex-specific association in the UK Biobank

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Ensuring adequate magnesium intake through diet or supplementation may support metabolic health, though more research is needed to determine if this specifically complements the therapeutic effects of GLP-1 medications

Report suspected adverse reactions via the MHRA Yellow Card scheme to support ongoing medication safety monitoring