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Stenzl, A
If the sequence homology is close, then you can perform a pilot test
However, there is no definitive evidence of efficacy in humans, and its status remains investigational pending rigorous clinical research
-KG can also be exported to the cytosol to be carboxylated into citrate through isocitrate dehydrogenase 1 (IDH1) and further into acetyl-CoA for de novo fatty acid synthesis (Fendt et al., 2013)
Protein oxidation is another detrimental effect of elevated ROS levels
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