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Prioritize protein and reduce fat
Serious adverse events like pancreatitis or gallbladder disease are rare but documented patients with a personal or family history of medullary thyroid carcinoma should not use GLP-1 agonists
Another important factor was it had the capacity to bind to albumin, a large protein common in the bloodstream, which would make the GLP-1 molecule too large to be quickly cleared by the kidney
The evolving role of investigative toxicology in the pharmaceutical industry
The references below summarise the mechanism-of-action and translational rat-model evidence base most relevant to the orthopedic and connective-tissue repair claims discussed in this article
