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its backed by extensive adverse-event reports from the FDA briefing document
Orforglipron, developed by Eli Lilly, is the first non-peptide oral GLP-1 agonist, achieving up to 1.8% HbA1c reduction and 1012% body-weight loss in Phase 3 trials
2013;5(209):209ra151
When used with insulin or sulfonylureas, these medications may increase hypoglycemia risk, requiring dose adjustments of those agents
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