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Chromone-derived PDE10 inhibitors (Compound 68 ) show high metabolic stability (rat microsomal, t: 105 min) and strong selectivity, with C-6 substitution improving potency and stability but requiring careful control to avoid solubility loss (Yu et al., 2020)
Evidence for a carrier-mediated process
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Vitamin B-12 Vitamin B-12 is crucial for red blood cell production, DNA synthesis, and neurological health
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