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You may already know that glutathione (GSH) is considered the most important antioxidant in the human body
We know that glutathione plays an important role in human, animal, and plant health
Furthermore, studies in rodents have suggested that GLP-1 analogs can act upon brain to suppress appetite without causing nausea, which is otherwise known to be among the most common side effects of todays GLP-1 therapies
Global analysis of the mitochondrial proteome in response to cellular GSH depletion To identify mitochondrial proteins regulated by GSH availability, we used quantitative proteomics and analyzed mitochondria immunopurified from HeLa cells expressing a mitotag (3XHA-OMP25-mCherry) grown in standard media or treated with the glutathione synthesis inhibitor, buthionine sulfoximine (BSO) 13
PMID 8365048
