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They don't typically cause the same kind of facial purging because they're not being applied directly to congested facial skin

The solution is straightforward: take creatine with food, use a micronized form for better dissolution, and avoid loading protocols (more on this below)

Data availability The authors declare that all data supporting the findings of this study are provided in the Manuscript and its Supplementary Information/Source Data files

Results differ for everyone

Middle East Fertil Soc J 28:16 Rezgoun ML, El Khour D, Bendaoud H, Chellat D (2023) CYP17A1 (rs74357) polymorphism and polycystic ovary syndrome risk: a systemic review and meta-analysis