One factor with any peptide is immunogenicity, which is an unintended immune response to the therapy
While existing evidence guides some aspects, more clinical research is needed to understand the long-term effects of semaglutide on gastrointestinal health, including colonoscopy outcomes
Frequently Asked Questions About GLP-1 Drugs and Optic Nerve Damage What is non-arteritic anterior ischemic optic neuropathy (NAION)
210,211 The weight loss effects from GLP-1 RA treatment may reverse these changes and alter the pharmacokinetics of co-administered lipophilic drugs by decreasing the Vd (Figure 3)
MJD reported payment for lectures or speaker bureaus from Novo Nordisk, Sanofi-Aventis, Lilly, Merck, Sharp & Dohme, Boehringer Ingelheim, AstraZeneca, Janssen, Mitsubishi Tanabe Pharma, and Takeda Pharmaceuticals International