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IPF as a Geroprotector Testbed IPFs rapid progression and measurable endpoints (e.g., FVC decline) make it ideal for evaluating anti-aging interventions
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These effects have not been linked to retatrutide in current trials
Mice were treated subcutaneously at the indicated doses with 5 l per g body weight of either Vehicle, Lani (CAS: 927961-18-0, MedChemExpress), semaglutide, GLP-1Lani, GLP-1Tesa, GLP-1GIP, GLP-1GIPTesa, GLP-1GIPLani, or co-administration of either GLP-1GIP plus Lani or GLP-1Lani plus acyl-GIP (Extended Data Fig