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Similarly, administration of a broad-spectrum MMP inhibitor (BB-1101) in hypertensive rats subjected to transient MCAO prevented increased BBB permeability to ( 14 C)-sucrose and blocked the degradation of claudin-5 and ZO-1 [100]
Exenatide ( n = 2, EXSCEL [17]), ITCA 650 [9]
CJC-1295 dosing varies based on formulation
Together, these peptides mimic the bodys natural growth hormone cycles
The medication creates a pronounced peak-and-trough cycle within each 24-hour period
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