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Dihexa Frequently Asked Questions Dihexas therapeutic value lies in its ability to promote the development of fresh, functional synaptic connections between existing neurons, the replacement of lost or damaged neurons with available neural stem cell populations, better cerebral blood flow, and the protection of the brain and prevention of disorders that could threaten it

10.1016/j.orcp.2021.02.002 45 RothM.OrijaI

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likewise suggests that the peptide may upregulate VEGF, raise endothelial cell proliferation, and encourage endothelial migration and tube formation

This review provides a detailed overview of the structural and synthetic strategies employed in developing PDE1B, PDE10A, and dual PDE1/10 inhibitors, with a focus on their binding sites and structureactivity relationships (SARs)