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EMERGING RESEARCH: WHAT THE SCIENCE SAYS While we are still awaiting large-scale clinical trials specifically for lipedema, recent pilot studies and reviews are promising: The "Italian Pilot Study" (Exenatide): A recent pilot study looked at women with lipedema and insulin resistance treated with a GLP-1 agonist (exenatide)

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It increased cellular 'stemness' and activated multiple repair pathways simultaneouslysuggesting it works as a broad biological reset signal