As clinicians (even non-prescribing clinicians), I think we need: - Curiosity - An understanding of how it might impact our rehab program design Better evidence, not anecdotes (the studies are mostly animal based) Conversations, not blank stares Because whether we like it or not, this isnt fringe anymore
Supplementing with injectable glutathione can boost cellular glutathione levels significantly
As seen in Figure 5, DEM administration severely depleted mucosal GSH by 1 hour to levels similar to those of TNBS+ethanol-treated rats
J Neurochem 102:170178 Kiskinis E, Sandoe J, Williams LA et al (2014) Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1
For a 5mg vial: Add 2.5ml bacteriostatic water Resulting concentration: 2mg/ml (2000mcg/ml) For a 100mcg dose: draw 0.05ml (5 units on a standard insulin syringe) For a 200mcg dose: draw 0.10ml (10 units) For a 10mg vial: Add 3.0ml bacteriostatic water Resulting concentration: 3.33mg/ml (3333mcg/ml) For a 100mcg dose: draw 0.03ml (3 units) For a 200mcg dose: draw 0.06ml (6 units) Alternatively, for easier math with a 5mg vial, you can add 5ml of bacteriostatic water to create a 1mg/ml (1000mcg/ml) concentration