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Rather than acting as a growth hormone fragment like AOD-9604 or a receptor agonist like Semaglutide GLP-1 S, tesamorelin works upstream in the GH axis prompting the bodys own pituitary to release growth hormone rather than introducing a growth hormone-derived compound directly

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GLP-1 medications are not proven to directly treat acne, but the weight loss and improved insulin sensitivity they produce may indirectly benefit some patients by reducing androgen levels and sebum production

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