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Constipation is less dose-dependent and can persist, making it a more durable reason for discontinuation in patient reports. Sulfur burps reflect food sitting longer in a slowed stomach. Fatigue ranks second only to nausea in patient forums, although much of it tracks the calorie deficit rather than tirzepatide itself. Fried or fatty foods, coffee, meat, and alcohol can also become less appealing

They just require strategy

The AACE guidelines recommend metabolic panel monitoring at baseline and periodically during treatment [8]

Make sure to consult your personal physician with any questions

You have type 2 diabetes that isn't adequately controlled by other medications