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It does not appear to interact negatively with other medications and has been well-tolerated across a wide range of doses in animal models

Food supplements are not a substitute for a balanced, varied diet and healthy lifestyle

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[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy

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