Complementary, holistic, and integrative medicine: melatonin [PMID: 19487431] Laboratory literature summary: Complementary, holistic, and integrative medicine: melatonin
In solid tumors, persistent antigen exposure and microenvironmental stress drive impaired ADP coupled oxidative phosphorylation, oxidative damage, reduced mitophagy and accumulation of dysfunctional mitochondria, which promote terminal exhaustion and limit persistence (187)
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Garcia-Navas et al., 2012)