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Acknowledgements This work was supported by grants from the National Research Foundation of Korea (NRF-2015M3A9E6028674, NRF-2016R1A5A1010764, and NRF-2017M3A9D8064193), the Institute for Basic Science from the Ministry of Science, ICT, and Future Planning of Korea (IBS-R008-D1), and Suh Kyungbae Foundation

MEAs recordings and analysis Recordings of neuronal electrophysiological activity were performed with 24-well MEAs (Multichannel systems) (24 independent wells with 12 embedded microelectrodes, 30 m in diameter and spaced 200 m apart) covered with a Breathe Easier sealing membrane (Sigma Aldrich)

This unique origin makes it a primary signaling molecule that facilitates communication from the mitochondriathe cells energy-producing organellesto the rest of the cell and, indeed, the entire body

Current Pharmaceutical Design , 19 (1), 7683

This research-grade solution is commonly used in laboratory settings for reconstituting lyophilized peptide compounds