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Both produce sustained, dose-dependent increases in both GH and IGF-1 without significantly altering other pituitary hormones such as prolactin, FSH, LH, or TSH
Data availability The mass spectrometry data generated in this study have been deposited in the Proteomexchange database under accession code PXD049973 and are freely accessible
The two LHR and FSHR are receptors associated with G protein, which transmit intracellular cascade through cAMP adenylate cyclase activity, and PKA activation, after which the CREB transcription factor is phosphorylated
[PMID: 29411341] Laboratory literature summary: Does IGF-1 play a role in the biology of ovarian oncology research models
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