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But we also see the high cholesterol levels that come from extreme meat-heavy diets
By inhibiting the naturally occurring enzyme PDE4, which degrades cAMP, with the drug roflumilast they showed that they could skew neurons toward a sustained response
Nature 2018;556:426-8
The plaque can either cause the vessels to be narrowed, which inhibits blood flow, or it can cause a clot to break off in another part of the body and travel to smaller vessels near the brain where it causes blockage
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