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However, there are a few downsides to consider: Invasive: Receiving regular injections may be uncomfortable for some people, as it requires visiting a clinic or performing self-injections
Lehnerer et al
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According to StatPearls (NCBI Bookshelf), the most common adverse effect of intramuscular vitamin B12 injections is significant pain at the injection site, which is particularly noted in thinner individuals
Signals are compelling enough to demand conversation and monitoring, even if definitive rules are not established
