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Clinical trials show that starting low reduces nausea rates by up to 40% compared to higher initial doses, making the first weeks more tolerable
Chemokine Receptor CCR1 Antagonist CCX354-C Treatment for Rheumatoid Arthritis: CARAT-2, a Randomised, Placebo Controlled Clinical Trial
Leptin levels drop, increasing hunger signals
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O.LarssonT.et al (2013)
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