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Lin EHB, Von Korff M, Alonso J, Angermeyer MC, Anthony J, Bromet E, et al
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Monitoring Response Patients or research participants typically notice: Appetite suppression within the first 12 weeks Early satiety and slower gastric emptying by weeks 34 Weight loss trends becoming evident by week 8 Continued improvements in glucose metabolism when paired with semaglutide or tirzepatide Side Effects and Considerations Common side effects include: Nausea Mild gastrointestinal discomfort Constipation Injection site reactions These effects are generally transient and dose-dependent, which is why titration is important
The diagnosis of MC is mainly based on the observation of brown pigment deposits in the colorectal mucosa under the microscope or the presence of brown granules in the cytoplasm of submucosal macrophages
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