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Besides the effects of GLP-1RAs on macrophage polarization into the M2 phenotype and on foam cell formation, GLP-1RAs may act directly on endothelial cells and limit endothelial dysfunction, which is primarily characterized by a reduction in nitric oxide (NO) bioavailability [46, 47]
Accessed December 5, 2025
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Atherothrombosis and Oxidative Stress: Mechanisms and Management in Elderly
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