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Naresh Kanumilli: No competing interests
Mitochondrial dynamics, including fusion and fission, respond to changes in the intracellular and extracellular environment by regulating mitochondrial size, number, and localization, thereby affecting both ROS production/clearance and organismal adaptive capacity
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IGF-DES Potency vs Native IGF-1 Studies using cultured cells confirmed that the biological potencies of IGF-1, IGF-2, and des-(1-3)-IGF-1 correlate inversely with their binding to IGFBP proteins in conditioned media establishing that des-(1-3)-IGF-1s enhanced in vivo and in vitro potency is a direct consequence of reduced IGFBP sequestration rather than greater intrinsic receptor affinity
Papaioannou A, Liakopoulou A, Papoulis D, Gianni E, Gkolfi P, Zygouri E
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