tirzepatide cardiovascular outcomes trial results august 2025 60-Second Journal Club: The SUMMIT examined of treatment with in patients with heart failure with preserved ejection fraction and obesity. Read the full trial SURPASS-CVOT Published: Large Trial Confirms

Semaglutide treatment at a dose of 1 mg weekly resulted in an 11 kg weight reduction over nine months, followed by an additional 7 kg weight loss over the next eleven months, once the dosage was elevated to 2 mg weekly

Individuals taking L-carnitine as a sports supplement to improve fat metabolism and muscular performance should stop using it at least for one week each month

Nausea Nausea is the most commonly reported tirzepatide side effect

But cellular repair does not make for a flashy Instagram post

Lower concentrations around 0.05% are suitable for maintenance and sensitive skin, while higher concentrations closer to 0.5% may be more effective for treating deeper wrinkles or post-procedure recovery