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doi: 10.1182/bloodadvances.2024013408 13

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Raghu G, Anstrom KJ, King TE Jr, Lasky JA, Martinez FJ

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E.RothmanR

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Astaxanthin has become one of the most talked-about skin antioxidants in recent years, promoted as a supplement that can reduce wrinkles, brighten skin, and even protect against UV damage

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84 The initial hypothesis that inducible nitric oxide synthase (iNOS) in Kupffer cells is a significant source of NO formation 85 was quickly dismissed, as iNOS was not consistently induced in different models 86 and iNOS inhibitors did not provide protection

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