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Patients who develop any of the above symptoms during retatrutide treatment should contact their GP promptly rather than waiting for a scheduled review
This helps to reduce the amount of sugar that is absorbed from your food
If genuine tachyphylaxis is confirmed, strategies include dose escalation to the next tier, brief treatment breaks of 2 to 4 weeks to allow receptor resensitization, or switching to alternative GLP-1 agonists like semaglutide to provide different receptor activation patterns
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