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Impaired Absorption, Distribution, Metabolism, and Excretion of Nutrients and Other Substances Impaired digestion can lead to impaired ADME (absorption, distribution, metabolism, and excretion of nutrients), and acid reflux, as the digestive tract no longer becomes able to optimally carry out its functions

As estrogen declines through perimenopause and into menopause, women lose an estimated 30% of dermal collagen in the first five years after their final menstrual period, with continued loss of roughly 2% per year thereafter

Tienen un mecanismo especfico para facilitar este proceso (piense en GR)

10.3389/fmed.2022.955560 23 DominguesR

Integration: Optimize diabetes control first (6-12 months achieving target HbA1c)