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Rare but serious effects can include pancreatitis, gallbladder problems, kidney injury (often linked to dehydration from severe vomiting or diarrhea), severe or persistent abdominal pain, serious allergic reactions, worsening of diabetic retinopathy in people with type 2 diabetes, and low blood sugar especially if semaglutide is combined with insulin or sulfonylureas

or kidney problems - little or no urination

PMID: 7342494