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Based on CMS Medicare Part D Spending by Drug, GLP-1 utilization has increased by approximately 46% annually since 2018 (Compound annual growth rate or CAGR)
Semaglutide has also reduced those same events
PMID 10613839
The authors noted limitations including reliance on ICD codes to identify NAION, lack of data on diabetes duration prior to Medicare enrollment, and a restricted age range that may limit generalizability
At concentrations between one and ten nanomolar, GHK-Cu stimulates both collagen and glycosaminoglycan synthesis while regulating the metalloproteinases (TIMP-1 and TIMP-2) responsible for balancing tissue breakdown and repair
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