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For many individuals, six months represents an ideal duration that provides substantial benefits without requiring annual commitments

GHK-Cu is the rational primary choice for users with sensitive or reactive skin, those with a history of retinoid intolerance, individuals managing rosacea or compromised barrier function, and anyone specifically targeting skin density, firmness, and hydration rather than primarily pigmentation and surface texture

Infection risk: Though the benzyl alcohol preservative inhibits bacterial growth in the vial, any lapse in sterility (dirty needle, etc.) can introduce pathogens

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Front Plant Sci 7:1299