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These systems metabolize and scavenge for reactive oxygen species, in a controlled and precise fashion

Most users do well, but possible effects include GI fullness, heartburn, changes in stool pattern, and rare allergic reactions (particularly to marine-derived products)

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It is real for a subset of users, and regulators have responded: the FDA added persistent sexual dysfunction to the label and, in 2022, agreed to list suicidal ideation as an adverse reaction